Most procollagen products on the market focus on the protection of already synthesized collagen against enzymatic degradation. In ageing skin, however, there is a greater degree of synthesis of incomplete collagen, which must be that, with age, there is a poorly controllable overall decline in its synthesis (Fligiel et al. 2003). The result is wrinkled, drooping skin. Glutaprol is an esteriﬁed form of α-ketoglutarate, which is a natural cofactor in the hydroxylation of proline in the cell. Proline is a key component of collagen fibres and its sufficient hydroxylation is essential for the successful completion of synthesis and the subsequent correct conformational arrangement of the entire collagen fibre.